Silat Lagenda 1998 Movie 13

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Silat Lagenda 1998 Movie 13

16 Oct 1998 | Featured Movie Info.Hereditary persistence of fetal hemoglobin is protective for stroke in chronic kidney disease.

The mechanism by which erythropoietin-stimulated erythroid cells secrete increased levels of fetal hemoglobin (HbF) is unclear. The most likely mechanism is a shift toward erythroid differentiation. This study was conducted to examine the association between HbF levels and clinical outcomes in patients with chronic kidney disease (CKD). We performed a retrospective analysis of a single center cohort of 259,512 patients with CKD. The patients were divided into 3 groups according to HbF levels: no HbF, HbF greater than 10%, and HbF less than 10%. We assessed the rates of major cardiovascular events (MACE), any stroke, and mortality in the 3 groups. Analyses were adjusted for ***, age, glomerular filtration rate, estimated glomerular filtration rate, diabetes mellitus, hypertension, hyperlipidemia, myocardial infarction, congestive heart failure, ischemic heart disease, cerebrovascular diseases, atrial fibrillation, previous cardio- or cerebrovascular events, and CKD complications. The proportion of men was higher in the group with HbF less than 10% than in the other 2 groups. The rate of MACE was significantly higher in the no HbF group than in the other 2 groups. The MACE rate was highest in the group with HbF less than 10%. The rate of any stroke was significantly lower in the group with HbF less than 10% than in the other 2 groups. The rate of any stroke was also significantly higher in the group with HbF greater than 10% than in the no HbF group. The higher HbF levels increased in the peripheral blood correlated with lower rates of MACE and any stroke in patients with CKD.*\*\*\*](#t005fn002){ref-type="table-fn"} 0b46394aab

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