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In the present study, we analyzed the morphological, developmental, and imaging features of schizencephaly. The morphological features of the skull base were analyzed from CT and MRI images, as well as the localization of the lesions. If the lesion was located in the basal ganglia, we analyzed the presence of other intracranial fluid-filled spaces and their respective imaging features, such as shape, size, intensity or signal and their contrast enhancement.
Aims of the study was to analyze the morphological, developmental and imaging features of schizencephaly, in order to increase the awareness of the radiologists. We analyzed the skull base configuration, the outer and inner cranial walls, and the location of the lesions. We also analyzed the presence of associated intracranial abnormalities, such as other fluid-filled spaces, and their peculiar imaging features.
Images were reviewed retrospectively. For the purpose of the study we have divided schizencephaly into two types: I (laminar) type and type II (open-lip). Type I schizencephaly is defined by the presence of well-defined incompletely delineated cortex from gray-white junction to the inner table of the calvarium, with a smooth convexity of the outer surface. Type II schizencephaly is defined by the presence of incompletely delineated cortex from gray-white junction to the inner table of the calvarium, with a flat concavity of the outer surface.
We also believe that the findings described in this paper may be useful in daily radiological practice to help understand clinical and pathological variety of CNS lymphomas as well as importance of immunophenotyping in daily diagnostics.
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